Fetuses make a protein that causes morning sickness in pregnancy

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Desensitizing people to the protein before pregnancy or blocking its action may help

A woman with long dark hair wearing a white T-shirt holds her right hand over her mouth while her left hand braces her against the wall. The image conveys nauseousness.Nausea and vomiting are common during pregnancy. Researchers have found a major driver of the illness, which can sometimes be severe enough to require hospitalization.</p>&#xA;" data-image-description="" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="122023_ti_morning_sickness_feat" data-large-file="https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?fit=800%2C450&ssl=1" data-medium-file="https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?fit=680%2C383&ssl=1" data-orig-file="https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?fit=1440%2C810&ssl=1" data-orig-size="1440,810" data-permalink="https://www.sciencenews.org/122023_ti_morning_sickness_feat" decoding="async" height="580" sizes="(max-width: 1030px) 100vw, 1030px" src="https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?fit=1030%2C580&ssl=1" srcset="https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?w=1440&ssl=1 1440w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=680%2C383&ssl=1 680w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=800%2C450&ssl=1 800w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=330%2C186&ssl=1 330w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=768%2C432&ssl=1 768w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=1030%2C580&ssl=1 1030w, https://i0.wp.com/www.sciencenews.org/wp-content/uploads/2023/12/122023_ti_morning_sickness_feat.jpg?resize=1380%2C776&ssl=1 1380w" width="1030">

Nausea and vomiting are common during pregnancy. Researchers have found a major driver of the illness, which can sometimes be severe enough to require hospitalization.

bymuratdeniz/E+/Getty Images

A surge of a hormone made by fetuses triggers the stomach-turning nausea and vomiting of morning sickness, a new study suggests.

People who have naturally low levels of the protein in their blood before pregnancy are more susceptible to a severe form of morning sickness called hyperemesis gravidarum when hit with the rush of protein, researchers report December 13 in Nature.

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