‘Grey’s Anatomy’ Season 21 Teaser: Jackson Avery Returns As Trouble Brews At Grey Sloan — Watch

Things aren’t looking great for the doctors at Grey Sloan Memorial Hospital.

A teaser for the upcoming 21st season of Grey’s Anatomy hints that Catherine Fox (played by Debbie Allen) is on a mission to overhaul the hospital after everyone’s jobs were left in limbo in the previous season finale.

In the final moments of Season 20, Miranda Bailey (Chandra Wilson) puts herself in the line of fire with Catherine to protect her interns. And in the trailer released this week, Bailey isn’t done there, slapping Catherine across the face when she calls her “just another doctor.”

Meredith (Ellen Pompeo), Amelia (Caterina Scorsone) and Teddy (Kim Raver) are also on the outs after Teddy agreed to secretly continue funding the Alzheimer’s research that Catherine had tried to shut down. It looks like Meredith will be recruiting the help of her son, Jackson Avery (Jesse Williams) to get back in her good graces, per the trailer.

Watch the entire clip above.

Though they aren’t in the teaser, expect to see the return of Scott Speedman, who plays Meredith’s love interest Nick Marsh, as well as Jason George’s Ben Warren in Season 21. Kali Rocha is also set to reprise her role of Sydney Heron 17 years after she last appeared on the show.

Season 21 arrives September 26 at 10 p.m. on ABC.